sickle cell

noun

: an abnormal red blood cell of crescent shape

Examples of sickle cell in a Sentence

Recent Examples on the Web

People with sickle cell trait are at higher risk for rhabdomyolysis. — News Editor, CBS News, 3 Nov. 2026

In July, the FDA approved the first gene therapy for children as young as two with sickle cell disease and awarded grants to expand access to care. — ABC News, 16 Oct. 2026

More broadly, efforts to create a more robust sickle cell disease care network nationally has been the work of the National Alliance of Sickle Cell Centers, of which sickle cell centers at both UAB and MUSC are participating members. — Steven Ross Johnson, CNBC, 16 Oct. 2026

Both Lloyd and Plancher experienced complications of sickle cell trait. — Michael McCann, Sportico.com, 30 Sep. 2026

Word History

First Known Use

circa 1923, in the meaning defined above

Rhymes for sickle cell

• bagatelle
• calomel
• caravel
• carousel
• carrousel
• citadel
• clientele
• commonweal
• coronel
• decibel
• demoiselle
• fontanelle

Kids Definition

sickle cell

noun

: an abnormal red blood cell that is crescent-shaped

Medical Definition

sickle cell

noun

1

: an abnormal rigid, sticky red blood cell of crescent shape

2

: a condition characterized by sickle cells : sickle cell anemia, sickle-cell trait