sickle cell

noun

: an abnormal red blood cell of crescent shape

Examples of sickle cell in a Sentence

Recent Examples on the Web

That changed when regulators approved Casgevy (exa-cel), the first medicine to use CRISPR gene editing to treat sickle cell disease and transfusion-dependent beta thalassemia. — Kaif Shaikh, Interesting Engineering, 27 July 2026

Agios Pharmaceuticals is discontinuing the development of a next-generation drug called tebapivat for sickle cell disease. — Elaine Chen, STAT, 21 July 2026

In the case of sickle cell disease, the hope is that developing nations with larger sickle cell populations will be able to use the FDA’s approval to approve the product for use in their own countries. — C. Michael White, The Conversation, 15 July 2026

In the lawsuit, Dickey’s parents alleged that Bucknell athletic trainers and coaches knew their son had sickle cell trait and failed to take steps to ensure precautions were in place. — Steve Henson, Los Angeles Times, 8 July 2026

Word History

First Known Use

circa 1923, in the meaning defined above

Rhymes for sickle cell

• bagatelle
• calomel
• caravel
• carousel
• carrousel
• citadel
• clientele
• commonweal
• coronel
• decibel
• demoiselle
• fontanelle

Kids Definition

sickle cell

noun

: an abnormal red blood cell that is crescent-shaped

Medical Definition

sickle cell

noun

1

: an abnormal rigid, sticky red blood cell of crescent shape

2

: a condition characterized by sickle cells : sickle cell anemia, sickle-cell trait